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ALDH2 modulator 1

CAS No. 1629615-99-1

ALDH2 modulator 1( —— )

Catalog No. M36013 CAS No. 1629615-99-1

ALDH2 modulator 1 is a potent, orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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2MG	147	Get Quote
5MG	278	Get Quote
10MG	440	Get Quote
25MG	702	Get Quote
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100MG	1287	Get Quote
500MG	2601	Get Quote
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Biological Information

Product Name

ALDH2 modulator 1
Note

Research use only, not for human use.
Brief Description

ALDH2 modulator 1 is a potent, orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.
Description

ALDH2 modulator 1 is a potent and orally active aldehyde dehydrogenase-2 (ALDH2) modulator. ALDH2 modulator 1 reduces blood alcohol levels in mice.
In Vitro

——
In Vivo

Animal Model:8-9 weeks, 20-22 g, Male C57BL6 mice (treated with PO 5/kg of EtOH) Dosage:40, 60 mg/kg for p.o. or 10 mg/kg for i.v.Administration:P.o. or i.v.Result:Reduced blood alcohol levels in mice treated with PO 5 g/kg of EtOH.
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Dehydrogenase
Recptor

Dehydrogenase
Research Area

——
Indication

——

Chemical Information

CAS Number

1629615-99-1
Formula Weight

364.8
Molecular Formula

C18H18ClFN2O3
Purity

>98% (HPLC)
Solubility

——
SMILES

O(CC1CC1)C2=C(C(NCC3=CC(F)=C(OC)C=C3)=O)C(Cl)=CC=N2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Wenjin Yang, et al. Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof. WO2014160185A2.

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